Name: Calum Roberts
Job Title: Consultant Neonatologist, Monash Children’s Hospital, Melbourne, Australia
Title of talk: The HIPSTER Trial: High Flow as Primary Respiratory Support for Preterm Infants
Biographical Sketch: Calum Roberts is a neonatologist from Scotland, who completed his training in the UK and in Melbourne, Australia. He has held consultant posts in Middlesbrough, and for the Victorian neonatal retrieval service, before taking his current position at Monash Children’s Hospital. Calum’s PhD study, completed at The Royal Women’s Hospital in Melbourne, was based on the use of nasal High Flow treatment in preterm infants. In addition to his clinical post, he holds a research appointment with Monash University, with a focus on neonatal resuscitation and respiratory support.
Lecture Abstract: The HIPSTER Trial, an international multi-centre non-inferiority study, conducted in Australia and Norway, is the largest published randomised trial of High Flow in neonates. Preterm infants of 28 weeks’ gestation and above, who had not been intubated or received surfactant treatment, were randomised to either High Flow or CPAP as primary treatment for early respiratory distress. The primary outcome of the trial was treatment failure, defined by pre-specified oxygenation, blood gas and apnoea criteria, or need for urgent intubation. This lecture will cover the results of the trial, including the primary outcome and other important outcomes, and will discuss how these findings can be interpreted into practice.
References: Roberts CT, Owen LS, Manley BJ, et al. Nasal High-Flow Therapy for Primary Respiratory Support in Preterm Infants. N Engl J Med 2016;375:1142-51